Which statement about CIN is true?

Which statement about CIN is true?

• A. It is a benign, non-progressive lesion
• B. It is a pigmented lesion arising from nevus
• C. It is caused by bacterial infection
• D. It is a conjunctival neoplasia that can progress to squamous cell carcinoma

Answer: (D)

Conjunctival intraepithelial neoplasia is a dysplastic change confined to the surface epithelium of the conjunctiva, and it has the potential to progress to invasive squamous cell carcinoma. This is why it’s described as a conjunctival neoplasia that can become squamous cell carcinoma. It’s not simply benign or non-progressive, and it’s not typically a pigmented lesion arising from a nevus, nor is it caused by bacterial infection. In practice, CIN is treated to remove the abnormal epithelium and prevent invasion, often with surgical excision and adjuvant therapy as needed.

Conjunctival intraepithelial neoplasia is a dysplastic change confined to the surface epithelium of the conjunctiva, and it has the potential to progress to invasive squamous cell carcinoma. This is why it’s described as a conjunctival neoplasia that can become squamous cell carcinoma. It’s not simply benign or non-progressive, and it’s not typically a pigmented lesion arising from a nevus, nor is it caused by bacterial infection. In practice, CIN is treated to remove the abnormal epithelium and prevent invasion, often with surgical excision and adjuvant therapy as needed.